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Transcriptome Resources

Transcriptomes of vector arthropods and non-vector, medically important arthropods and snakes

Overview

Salivary transcriptomes (sialome) of ticks
Salivary transcriptomes (sialome) of blood feeding insects
Non-blood feeding sialotranscriptomes
Whole Organism Transcriptome
Poisonous animals
ReAnoXcel: an Anopheles gambiae protein database [Maintained]
AnoXcel: an Anopheles gambiae protein database [Old Dataset - Dec 2004]
AegyXcel: an Aedes aegypti protein database
CuquiXcel: an Culex quinquefasciatus protein database
IscaXcel: an Ixodes scapularis protein database

Salivary transcriptomes (sialome) of ticks:

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Antricola delacruzi (Ribeiro JM, Labruna MB, Mans BJ, Maruyama SR, Francischetti IM, Barizon GC, deMiranda Santos IK. The sialotranscriptome of Antricola delacruzi female ticks is compatible with non-hematophagous behavior and an alternative source of food. Insect Biochem Mol Biol. 2012 May;42(5):332-42. Epub 2012 Jan 24). Argas monolakensis (Mans BJ, Andersen JF, Schwan TG, Ribeiro JM. (2008) Characterization of anti-hemostatic factors in the argasid, Argas monolakensis: Implications for the evolution of blood-feeding in the soft tick family. Insect Biochem Mol Biol. 38:22-41). Ornithodoros coriaceus (Francischetti IM, Meng Z, Mans BJ, Gudderra N, Hall M, Veenstra TD, Pham VM, Kotsyfakis M, Ribeiro JM. (2008) An insight into the salivary transcriptome and proteome of the soft tick and vector of epizootic bovine abortion, Ornithodoros coriaceus. J Proteomics. 71(5):493-512). Ornithodoros parkeri (Francischetti I.M., Mans B.J., Meng Z., Gudderra N., Veenstra T.D., Pham V.M., Ribeiro J.M. (2008) An insight into the sialome of the soft tick, Ornithodorus parkeri. Insect Biochem Mol Biol. 38:1-21). Amblyomma maculatum (Karim S, Singh P, Ribeiro JM. A deep insight into the sialotranscriptome of the gulf coast tick, Amblyomma maculatum. PLoS One. 011;6(12):e28525. Epub 2011 Dec 21.). Amblyomma variegatum (Ribeiro JM, Anderson JM, Manoukis NC, Meng Z, Francischetti IM. A further insight into the sialome of the tropical bont tick, Amblyomma variegatum. BMC Genomics. 2011 Mar 1;12:136). Hyalomma marginatum rufipes (Francischetti IM, Anderson JM, Manoukis N, Pham VM, Ribeiro JM. An insight into the sialotranscriptome and proteome of the coarse bontlegged tick, Hyalomma marginatum rufipes. J Proteomics. 2011 Nov 18;74(12):2892-908). Ixodes scapularis (Valenzuela, J. G., Francischetti, I. M. B., Pham, V. M., Garfield, M. K., Mather, T. N. and Ribeiro, J. M. C. (2002). Exploring the sialome of the tick, Ixodes scapularis. J. Exp. Biol. 205, 2843-64). Updated Ixodes scapularis sialome (José M. C. Ribeiro , Francisco Alarcon-Chaidez, Ivo M. B. Francischetti , Ben J. Mans, Thomas N. Mather , Jesus G. Valenzuela, and Stephen K. Wikel. (2006) An annotated catalog of salivary gland transcripts from Ixodes scapularis ticks. Insect Biochem Mol Biol.  36(2):111-29 Ixodes pacificus (Francischetti, I.M., Pham, V.M., Mans, B., Andersen, J.F., Mather, T.N., Lane, R.S. and Ribeiro, J.M.C. (2005) The transcriptome of the salivary glands of the female western black legged tick Ixodes pacificus (Acari: Ixodidae). Insect Biochem. Mol. Biol. 35, 1142-61. Rhipicephalus sanguineus (Anatriello E, Ribeiro JM, de Miranda-Santos IK, Brand?o LG, Anderson JM, Valenzuela JG, Maruyama SR, Silva JS, Ferreira BR.. (2010) An insight into the sialotranscriptome of the brown dog tick, Rhipicephalus sanguineus. BMC Genomics. 11:450).

Review article with tick salivary gland protein annotations:

THE ROLE OF SALIVA IN TICK FEEDING (Ivo M.B Francischetti1, Anderson S?-Nunes1, Ben J. Mans1, Isabel M. Santos2 and Jos? M.C. Ribeiro1 (2009) Frontiers in Bioscience 14, 2051-2088).

Salivary transcriptomes (sialome) of blood feeding insects:

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  • An insight into the sialome of blood-feeding Nematocera. (Ribeiro, J.M., Mans, B.J. and Arc? B. (2010) Insect Biochem Mol Biol. 40:767-84.).
  • Aedes aegypti (Valenzuela, J. G., Pham, V. M., Garfield, M. K., Francischetti, I. M. and Ribeiro, J. M. C. (2002). Toward a description of the sialome of the adult female mosquito Aedes aegypti. Insect Biochem. Mol. Biol. 32, 1101-1122).
  • Updated Aedes aegypti (Ribeiro, J.M.C., Arcà, B., Lombardo, F., Calvo, E., Phan, V.M., Chandra, P.K., Wikel, S.K. (2006). An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti. BMC Genomics. 2007 8:6)
  • Aedes albopictus (Arcà, B., Lombardo, F., Francischetti, I.M., Pham, V.M., Mestres-Simon, M., Andersen, J.F., Ribeiro, J.M. (2007) An insight into the sialome of the adult female mosquito Aedes albopictus. Insect Biochem Mol Biol. 37(2):107-27.)
  • Anopheles gambiae sialome (Francischetti, I. M., Valenzuela, J. G., Pham, V. M., Garfield, M. K. and Ribeiro, J. M. (2002). Toward a catalog for the transcripts and proteins (sialome) from the salivary gland of the malaria vector Anopheles gambiae. J. Exp. Biol. 205, 2429-51).
  • Updated Anopheles gambiae sialome (Bruno Arcà, Fabrizio Lombardo, Jesus G. Valenzuela, Ivo M.B. Francischetti, Mario Coluzzi and Jose M.C. Ribeiro (2005) An updated catalog of salivary gland transcripts in the adult female mosquito, Anopheles gambiae (2005) J. Exp. Biol. 208, 3971-86.
  • Anopheles gambiae male sialotranscriptome (Calvo, E. Pham, V.M. Lombardo, F., Arcà and Ribeiro, J.M.C. (2006). The sialotranscriptome of adult male Anopheles gambiae mosquitoes. Insect Biochem Mol Biol. 36(7):570-5.
  • Anopheles stephensi sialome (Valenzuela, J. G., Francischetti, I. M., Pham, V. M., Garfield, M. K. and Ribeiro, J. M. (2003). Exploring the salivary gland transcriptome and proteome of the Anopheles stephensi mosquito. Insect Biochem Mol Biol 33, 717-32).
  • Anopheles funestus sialome (Calvo, E., Dao, A., Pham, V.M., and Ribeiro, J.M.C. (2007). An insight into the sialome of Anopheles funestus reveals an emerging pattern in anopheline salivary protein families. Insect Biochem Mol Biol 37, 164-75).
  • Anopheles darlingi (Calvo, E., Andersen, J., Francischetti, I. M., de, L. C. M., deBianchi, A. G., James, A. A., Ribeiro, J. M. and Marinotti, O. (2004). The transcriptome of adult female Anopheles darlingi salivary glands. Insect Mol Biol 13, 73-88).
  • Anopheles darlingi expanded (Calvo E., Pham V.M., Marinotti O., Andersen J.F., and Ribeiro J.M. (2009) The salivary gland transcriptome of the neotropical malaria vector Anopheles darlingi reveals accelerated evolution of genes relevant to hematophagy. BMC Genomics. 10:57).
  • Culex pipiens quinquefasciatus (Ribeiro JM, Charlab R, Pham VM, Garfield M, Valenzuela JG. (2004). An insight into the salivary transcriptome and proteome of the adult female mosquito Culex pipiens quinquefasciatus. Insect Biochem Mol Biol. 2004 Jun;34(6):543-63.
  • Culex tarsalis (Calvo, E., Sanchez-Vargas, I., Favreau, A.J., Barbian, K.D., Pham, V.M., Olson, K.E. and Ribeiro J.M. (2010). An insight into the sialotranscriptome of the West Nile mosquito vector, Culex tarsalis. BMC Genomics. 11:51.
  • Ochlerotatus triseriatus (Calvo E, Sanchez-Vargas I, Kotsyfakis M, Favreau AJ, Barbian KD, Pham VM, Olson KE, Ribeiro JM. (2010). The salivary gland transcriptome of the eastern tree hole mosquito, Ochlerotatus triseriatus. J Med Entomol. 47:376-86.
  • Simulium vittatum (Andersen JF, Pham VM, Meng Z, Champagne DE, Ribeiro JM. (2009) Insight into the Sialome of the Black Fly, Simulium vittatum. J Proteome Res. Jan 23.)
  • Simulium nigrimanum (Ribeiro JM, Valenzuela JG, Pham VM, Kleeman L, Barbian KD, Favreau AJ, Eaton DP, Aoki V, Hans-Filho G, Rivitti EA, Diaz LA. (2010) An insight into the sialotranscriptome of Simulium nigrimanum, a black fly associated with fogo selvagem in South America. Am J Trop Med Hyg. 82:1060-75. Simulium guianense (Chagas AC, Calvo E, Pimenta PF, Ribeiro JM. An insight into the sialome of Simulium guianense (DIPTERA:SIMulIIDAE), the main vector of River Blindness Disease in Brazil. BMC Genomics. 2011 Dec 19;12:612).
  • Stomoxys calcitrans (Wang, X., Ribeiro, J.M.C., Broce, A.B., Wilkerson, M.J. and Kanost, M.R. (2009) An insight into the transcriptome and proteome of the salivary gland of the stable fly, Stomoxys calcitrans. Insect Biochem Mol Biol. 39:607-14.)
  • Glossina morsitans morsitans (Alves-Silva J, Ribeiro JM, Van Den Abbeele J, Attardo G, Hao Z, Haines LR, Soares MB, Berriman M, Aksoy S, Lehane MJ.. (2010) An insight into the sialome of Glossina morsitans morsitans. BMC Genomics. Mar 30;11:213.)
  • Cimex lectularius (Francischetti IM, Calvo E, Andersen JF, Pham VM, Favreau AJ, Barbian KD, Romero A, Valenzuela JG, Ribeiro JM. (2010). Insight into the Sialome of the Bed Bug, Cimex lectularius . J Proteome Res. 9:3820-31). Dipetalogaster maxima(Assump??o TC, Charneau S, Santiago PB, Francischetti IM, Meng Z, Ara?jo CN,Pham VM, Queiroz RM, de Castro CN, Ricart CA, Santana JM, Ribeiro JM. Insight into the salivary transcriptome and proteome of Dipetalogaster maxima. J Proteome Res. 2011 Feb 4;10(2):669-79. Epub 2011 Jan 4.).
  • Rhodnius prolixus Ribeiro, J.M., Andersen, J., Silva-Neto, M.A., Pham, V.M., Garfield, M.K. and Valenzuela, J.G. (2004). Exploring the sialome of the blood-sucking bug Rhodnius prolixus. Insect Biochem Mol Biol 34, 61-79).
  • Triatoma brasiliensis (Santos, A., Ribeiro, J.M., Lehane, M.J., Gontijo, N.F., Veloso, A.B., Sant'Anna, M.R., Nascimento Araujo R., Grisard, E.C., Pereira, M.H. (2007) The sialotranscriptome of the blood-sucking bug Triatoma brasiliensis (Hemiptera, Triatominae). Insect Biochem Mol Biol. 37:702-12).
  • Triatoma infestans (Teresa C. F. Assumpção, Ivo M. B. Francischetti, John F. Andersen, Alexandra Schwarz, Jaime M. Santana and José M. C. Ribeiro (2008) An insight into the sialome of the blood-sucking bug Triatoma infestans, a vector of Chagas' disease. Insect Biochem Mol Biol. In press).
  • Xenopsylla cheopis (Andersen, J.F., Hinnebusch, B.J., Lucas, D.A., Conrads, T.P., Veenstra, T.D., Pham, V.M., Ribeiro, J.M. (2007) An insight into the sialome of the oriental rat flea, Xenopsylla cheopis (Rots). BMC Genomics. 8:102.).

Non-blood feeding sialotranscriptomes:

 
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  • Oncopeltus fasciatus, a seed feeding Hemiptera closely related to triatomines. (Francischetti, I.M., Lopes, A.H., Dias, F.A., Pham, V.M., Ribeiro, J.M. An insight into the sialotranscriptome of the seed-feeding bug, Oncopeltus fasciatus. Insect Biochem Mol Biol. 37(9):903-10.)
  • Toxorhynchites amboinensis a non-blood feeding mosquito. (E. Calvo, V. M. Pham and J. M. C. Ribeiro. An insight into the sialotranscriptome of the non-blood feeding Toxorhynchites amboinensis mosquito Insect Biochem Mol Biol. In press)

 

Whole Organism Transcriptome:

 
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  • Anopheles gambiae transcriptome analysis from whole blood-fed and non-blood fed adult female mosquitoes, as reported in Ribeiro, J. M. (2003). A catalogue of Anopheles gambiae transcripts significantly more or less expressed following a blood meal. Insect Biochem. Mol. Biol. 33, 865-82.

Poisonous animals:

 
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ReAnoXcel: an Anopheles gambiae protein database

Maintained - Updated March 2009
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Improved Anopheles gambiae genome annotation through synthesis of ab initio and comparative gene prediction algorithms. Jun Li, Michelle M. Riehle, Yan Zhang, Jiannong Xu, Frederick Oduol, Shawn M. Gomez, Beatrix Ueberheide, Donald Hunt, Charles W. Roth, José M. C. Ribeiro, and Kenneth D. Vernick. S Genome Biol. 2006;7(3):R24

  • PMID: 16569258
  • The data set below refers to this new set of predicted genes, not ENSEMBL predictions.
  • ReAnoXcel-Feb-2006.zip [27.7 MB] – download and unzip the files onto your computer. There are two tab delimited files (.tab) that can be imported to other databases or can be browsed by importing into Microsoft Excel.
    • ReAnoXcel-lookup.tab [58629778 bytes] - tab delimited lookup table
    • ReAnoXcel-Feb-2006.tab [134122881 bytes] - tab delimited ReAnoXcel data table - update of ReAnoXcel-Jan-2006.tab to reinclude duplicate genes by duplicating the record of the duplicate sequence (only changing the display id).
    • ReAnoXcel-Jan-2009.zip [127 MB] – updated version

AnoXcel: an Anopheles gambiae protein database

 
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AegyXcel: an Aedes aegypti protein database

 
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  • This is a protein database from VectorBase Aedes aegypti proteins version 1.2 organized as in AnoXcel above
  • AegyXcelv1.2-Web.zip

CuquiXcel: a Culex quinquefasciatus protein database

 
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  • This is a protein database from VectorBase Culex quinquefasciatus proteins version 1 organized as in AnoXcel above
  • CuquiXcelv1-web.zip

IscaXcel: an Ixodes scapularis protein database

 
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  • This is a protein database from VectorBase Ixodes scapularis proteins version 1 organized as in AnoXcel above
  • IsXcelv1-Web.zip

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