Desktop cDNA Annotation System (dCAS) v1.4

Perform automated large-scale cDNA sequence analysis

CAS software screenshot

Install Instruction | Online Manual | Sample Data

The Desktop cDNA Annotation System (dCAS) automates large-scale cDNA sequence analysis. dCAS allows you to import raw cDNA sequences, clean sequences, build sequence contigs, perform SignalP analysis, BLAST contigs against numerous BLAST databases, and view the results in a Microsoft Excel worksheet. Manual curation of each gene can be performed in the excel file and then easily re-imported into the cDNA Annotation System. dCAS enables you to view, justify, and edit the 6-frame peptide translation. As a final step in the workflow, annotated genes and their corresponding translated products can be written into FASTA files for submission to GenBank.

What is new in Version 1.4?

EST uploading data preparation. A new utility is added to help users to prepare EST sequence data for dbEST submission.
TMHMM prediction: A new step, TMHMM 2.0, is added to the core workflow. The step is used to predict transmembrane helices in proteins.
dCAS Mate improvement: More stable and more error tolerant.
GenBlast improvement: Reprocessing can be started from the middle.
Statistics report: The generated Excel file contains a new worksheet to report the filtered sequence numbers in the workflow.
Report rearrangement: Column orders in the generated Excel files are changed. Excel files generated by version 1.3 can still be processed by version 1.4.
New software packaging and deployment: dCAS has an installer program for all platforms.
Software update features: dCAS automatically checks for updates when it is launched. Users can also manually check for new updates.
Memory usage improvement.