full-sized screen shots. )
The Hemagglutinin Structure Prediction (HASP) server was designed as a scientific tool for researchers to visualize their phylogenetic, biochemical, and immunological HA data in the three-dimensional context of the HA structure, in the hopes that the context may help researchers better interpret their data and generate new hypotheses. HASP provides high-quality homology models built using Rosetta for all publicly available hemagglutinin (HA) protein sequences. HASP presents the models in such a way that researchers can gain scientific insights directly through the application and can easily retrieve the structures for more intensive offline studies and analysis.
The web interface for HASP was developed using GWT. The gene information was extracted from NCBI GenBank annotations, and the proteins were modeled using Rosetta. The HASP framework can be easily adapted for displaying any protein structure data. We welcome your ideas for improvement and feedback; please contact us through the Support page.
- Interactive map based location search for searching by geographical region
- Select up to two models to be displayed directly in a built-in molecular viewer
- Interactive alignment to easily identify residues in the model
- Export the sequences in FASTA or the models in PDB format for further analysis
- HASP Server: A database and structural visualization platform for comparative models of influenza hemagglutinin proteins.